Featured Speakers

Keynote Lecture

Jeffrey Gordon, Washington University
The Human Microbiome

Plenary Talks

William E. Balch, The Scripps Research Institute
Managing Trafficking Disease through Proteostasis: a Proteomics View

Linda Hsieh-Wilson, California Institute of Technology
The Sweeter Side of Cell Signaling: New Insights into Protein Glycosylation

Nicholas Drapocoli, Ortho Biotech R&D, Johnson & Johnson
Personalized Medicine: From Biological Data to Clinical Applications
Garry Nolan, Stanford University
Cytometric Analysis of Signaling in Single Cells

J. Wade Harper, Harvard Medical School
Protein Interaction Landscapes in Deubiquitination and DNA Repair Norbert Perrimon, Harvard Medical School
Phosphorylation Networks and Orthogonal RNAi Screens

Invited Invited Speakers and their Tentative Titles for Concurrent and General Sessions

1. Biomarkers (Mon AM)

· Steven Carr, Broad Institute;Biomarker Discovery-to-Development Pipeline in Clinical Proteomics

· Sabine Bahn, University of Cambridge; CSF Biomarkers in Schizophrenia

2. Top Down Mass Spectrometry (Mon AM)

· Neil Kelleher, University of Illinois, Urbana-Champaign; Exploring the ‘PTM Code’ by Top Down Proteomics

3. Proteomics and Chemical Biology (Mon AM)

· Matthew Bogyo, Stanford University; Activity Based Probes for Enzymatic Markers

· Laura Kiessling, University of Wisconsin; Determinants of Length in Processive Enzymes

4. Glycoproteomics (Mon AM)

· Susan J. Fisher, UCSF; Cell Surface Glycoproteins in Tissue Remodeling

5. Profiling the Metabolome + Panel Discussion (Mon PM)

· Edward M. Driggers, Agios Pharmaceuticals; Targeting the Cancer Metabolome

· Gary Siuzdak, The Scripps Research Institute; Mass Spectrometry - Based Therapeutic Metabolomics of Biofluids and Tissues

· Robert Murphy, UCHSC Denver; Tissue Imaging of Lipids by Mass Spectrometry

6. Protein Interaction + Panel Discussion (Mon PM)

· Deborah Morrison, NCI Frederick; Signal Transduction Scaffolds

· Cammie Lesser, Harvard; Protein Interaction Platforms: Visualizing Living Cell Interactions

· Jack Greenblatt, University of Toronto; Systematic Characterization of Protein Interaction Networks

7. Profiling Human Diseases (Tues AM)

· Pei Pei Ping, UCLA; Metabolomics and Proteomics of Cardioprotection

8. Proteomic Technologies I (Tues AM)

· David Muddiman, North Carolina State University; New Ionization Methods for Large-Molecule Top-Down Mass Spectrometry

9. Post-translational Modifications (Tues AM)

· Yingming Zhao, University of Chicago; Discovery and Characterization of Protein Post-translational Modification Pathways

10. Proteomics Technologies II (Tues AM)

· Joshua LaBaer, Arizona State University, Biodesign Institute; Self Assembling Protein Microarrays

11. Proteomics and Clinical Diagnostics + Panel Discussion (Tues PM)

· Leigh Anderson, Plasma Proteome Institute; Quantifying Proteins in Plasma

· Kojo Elenitoba-Johnson, University of Michigan; Deciphering Deregulated Signaling Pathways in ALK-Positive Human Malignant Lymphomas

· Andrew Hoofnagle, University of Washington; Clinical Laboratory Assays by Quantitative Mass Spectrometry

· Ron Hendrickson, Merck Research Laboratories; Differential Mass Spectrometry (dMS): A Promising Strategy to Identify, Validate and Qualify Protein Based Biomarkers for New Medicines

12. Computational Mass Spectrometry and Bioinformatics + Panel Discussion (Tues PM)

· Keith Baggerly, MD Anderson; Forensic Bioinformatics

· Vicki H. Wysocki, University of Arizona, Tucson; Modeling Gas Phase Fragmentation

· Pavel Pevzner, UC San Diego; De novo Sequencing of Peptides

13. New Technologies (Wed AM)

· Rob Knight, U. Colorado at Boulder; Bacterial Community Variation in Human Body Habitats

14. Oxidative Stress (Wed AM)

· Allan Butterfield, University of Kentucky; Free Radical Oxidative Stress in Brain Subjects with Alzheimer's Disease: Central Role of Amyloid - Peptide (1-42) and Insights from Redox Proteomics

General session: Mass Spectrometry for the Masses (Wed AM)

· Nikolaus Rajewsky, Max Delbruck Inst. Berlin; Proteome Targets of microRNAs and RNA Binding Proteins

· Joshua Coon, University of Wisconsin; ETD Mass Spectrometry in Proteomic Analysis